Recent Publications in Women’s Mental Health

Recent Publications in Women’s Mental Health


HPA axis activity across the menstrual cycle – a systematic review and meta-analysis of longitudinal studies.

Klusmann H, Schulze L, Engel S, Bücklein E, Daehn D, Lozza-Fiacco S, Geiling A, Meyer C, Andersen E, Knaevelsrud C, Schumacher S.  Front Neuroendocrinol. 2022 May 18;66:100998.

Long J, Wang Y, Liu L, Zhang J. The Prominent Role of the Temporal Lobe in Premenstrual Syndrome and Premenstrual Dysphoric Disorder: Evidence From Multimodal Neuroimaging. Front Psychiatry. 2022 Jun 28; 13:954211.

Recent research have revealed some novel findings on PMS and PMDD primarily based on mind morphology, perform, and metabolism. Additionally, a number of research have instructed that PMS and PMDD are intently associated to mind structural and useful variations in sure core temporal lobe areas, such because the amygdala and hippocampus. 



No articles this week



Associations Between Implementation of the Collaborative Care Model and Disparities in Perinatal Depression Care.

Snowber Ok, Ciolino JD, Clark CT, Grobman WA, Miller ES.  Obstet Gynecol. 2022 Aug 1;140(2):204-211. 

Implementation of the perinatal collaborative care mannequin is related to a mitigation of racial disparities in antenatal despair care and could also be an equity-promoting intervention for maternal health.

Prevalence of Bipolar Disorder in Perinatal Women: A Systematic Review and Meta-Analysis.

Masters GA, Hugunin J, Xu L, Ulbricht CM, Moore Simas TA, Ko JY, Byatt N.  J Clin Psychiatry. 2022 Jul 13;83(5):21r14045.

In women with no recognized psychiatric sickness previous the perinatal interval, pooled prevalence of BD was 2.6% (95% CI, 1.2%-4.5%) and prevalence of bipolar-spectrum temper episodes (together with depressed, hypomanic/manic, blended) throughout being pregnant and the postpartum interval was 20.1% (95% CI, 16.0%-24.5%). In women with a previous BD analysis, 54.9% (95% CI, 39.2%-70.2%) had been discovered to have not less than one bipolar-spectrum temper episode incidence within the perinatal interval.

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Perspectives on addressing bipolar disorder in the obstetric setting.

Masters GA, Xu L, Cooper KM, Moore Simas TA, Brenckle L, Mackie TI, Schaefer AJ, Straus J, Byatt N.  Gen Hosp Psychiatry. 2022 Jul-Aug;77:130-140. 

Obsessive-compulsive and related disorder symptoms in the perinatal period: prevalence and associations with postpartum functioning.

Miller ML, Roche AI, Lemon E, O’Hara MW.  Arch Womens Ment Health. 2022 Aug;25(4):771-780.

OCRD signs happen throughout being pregnant and the postpartum interval at charges comparable or greater than different life durations. Elevated OCRD signs are related to poorer postpartum functioning throughout domains. 

Body dissatisfaction and disordered eating in the perinatal period: an underrecognized high-risk timeframe and the opportunity to intervene.

Vanderkruik R, Ellison Ok, Kanamori M, Freeman MP, Cohen LS, Stice E.  Arch Womens Ment Health. 2022 Aug;25(4):739-751. doi: 10.1007/s00737-022-01236-6. Epub 2022 May 6.

Over 50% of the women surveyed on this examine had been dissatisfied with their physique picture. Approximately 80% reported that they might have appreciated the chance to take part in a program centered on physique acceptance or expectations of physique modifications in being pregnant and postpartum. We recognized intervention preferences in addition to generally reported themes concerning experiences of physique picture and consuming issues in being pregnant and postpartum. Body dissatisfaction and consuming issues are prevalent points in being pregnant and postpartum women.

Perinatal mental health literacy: knowledge, attitudes, and help-seeking among perinatal women and the public – a systematic review.

Daehn D, Rudolf S, Pawils S, Renneberg B.  BMC Pregnancy Childbirth. 2022 Jul 19;22(1):574. 

Based on the findings of this overview, there’s a want for academic campaigns and interventions to enhance perinatal MHL in perinatal women and the general public as a complete.

 Experiences with use of technology and telehealth among women with perinatal depression.

Parameswaran UD, Pentecost R, Williams M, Smid M, Latendresse G.  BMC Pregnancy Childbirth. 2022 Jul 18;22(1):571. 

This examine supplies rising proof knowledgeable by perinatal women of constructive experiences with engagement in a videoconference intervention for PD. Telehealth could also be an inexpensive and acceptable platform to extend entry and retention for psychological health companies in childbearing women. 

Web-based treatment for depression in pregnancy: a feasibility study of Mum2BMoodBooster.

Gemmill AW, Oliva JL, Ericksen J, Holt C, Holt CJ, Milgrom J.   BMC Psychiatry. 2022 Jul 16;22(1):476.

In this feasibility trial, despair scores on each the PHQ-9 and the DASS-21, confirmed important reductions representing massive results, with common symptom scores diminished by > 50%, and maintained within the ‘minimal or no depression’ vary at 3 month follow-up. 



Neurobehavioral follow-up of children exposed to selective serotonin reuptake inhibitors in utero.

Cohen LS, Rhodes SM, Claypoole LD, Góez-Mogollón L, Sosinsky AZ, Moustafa D, Noe OB, McElheny SA, Cheng LJ, Bick JR, Freeman MP, Nelson CA.  Ann Clin Psychiatry. 2022 Aug;34(3):197-206. 

No associations had been discovered between maternal use of selective serotonin reuptake inhibitors (SSRIs) throughout being pregnant and atypical neurodevelopment of kids. 

Pregnancy outcomes after first-trimester exposure to buspirone: prospective longitudinal outcomes from the MGH National Pregnancy Registry for Psychiatric Medications.

Freeman MP, Szpunar MJ, Kobylski LA, Harmon H, Viguera AC, Cohen LS.  Arch Womens Ment Health. 2022 Jul 16. 

Among this pattern of 72 infants with prenatal publicity to buspirone, there have been no malformations current.

The Pursuit to Recognize Bipolar Disorder in Pregnant and Postpartum Women.

Freeman MP, Goldberg JF.  J Clin Psychiatry. 2022 Jul 13;83(5):22ed14399.



The Effects of Breastfeeding on Maternal Mental Health: A Systematic Review.

Yuen M, Hall OJ, Masters GA, Nephew BC, Carr C, Leung Ok, Griffen A, McIntyre L, Byatt N, Moore Simas TA.  J Womens Health (Larchmt). 2022 Jun;31(6):787-807.

Interpersonal therapy versus antidepressant medication for treatment of postpartum depression and anxiety among women with HIV in Zambia: a randomized feasibility trial.

Spelke MB, Paul R, Blette BS, Meltzer-Brody S, Schiller CE, Ncheka JM, Kasaro MP, Price JT, Stringer JSA, Stringer EM.  J Int AIDS Soc. 2022 Jul;25(7):e25959. 

Impact of coronavirus 2019 pandemic on post-traumatic stress disorder symptoms among pregnant women in Jordan.

Bataineh MF, Mohamad MN, Al Dhaheri AS, Rawashdeh M, Al-Nawaiseh AM, Asali FF, Hashim M, Jarrar A, Abu Jamous DO, Stojanovska L, Daour RA, Saleh ST, Osaili TM, Cheikh Ismail L.  Womens Health (Lond). 2022 Jan-Dec;18:17455057221112935. 

IPT and antidepressant remedy each improved measures of despair severity; nonetheless, a full-scale trial is required to find out whether or not remedy of PPD and nervousness improves maternal-infant HIV outcomes.



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Impact of menstrual cycle events on bipolar disorder course: a narrative review of current evidence.

Aragno E, Fagiolini A, Cuomo A, Paschetta E, Maina G, Rosso G.  Arch Womens Ment Health. 2022 Apr;25(2):257-266.

This overview observes {that a} subset of women with bipolar dysfunction are weak to the affect of menstrual cycle occasions. Menarche appears to be related to age at onset of bipolar sickness particularly in case of bipolar dysfunction kind I and the particular age at menarche might predict some medical options of the dysfunction. Menstrual cycle doubtless impacts the course of bipolar dysfunction however the sample of temper variability just isn’t clear. Menopause seems to be not solely a interval of vulnerability to temper alteration, particularly depressive episodes, and impairment of high quality of life, but additionally a possible set off of bipolar sickness onset.



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Towards a new understanding of pregnancy denial: the misunderstood dissociative disorder.

Barnes DL.  Arch Womens Ment Health. 2022 Feb; 25(1):51-59. 

This overview concludes that dissociation is a constantly seen symptom in pervasive being pregnant denial.  The expertise of a dissociative episode whereas giving delivery can unintentionally lead to neonaticide. Dissociation, along with different generally seen signs throughout instances, suggests particular diagnostic standards that lend themselves to inclusion within the Diagnostic and Statistical Manual of Mental Disorders.



Antidepressant use during pregnancy and risk of adverse neonatal outcomes: A comprehensive investigation of previously identified associations.

Rommel AS, Momen NC, Molenaar NM, Agerbo E, Bergink V, Munk-Olsen T, Liu X.  Acta Psychiatr Scand. 2022 Jun;145(6):544-556. 

Prenatal antidepressant publicity was related to small decreases in gestational age and birthweight, in addition to greater threat for moderate-to-late preterm delivery, reasonably low birthweight, neonatal admission and postnatal adaptation syndrome. No variations in threat had been discovered for PPHN, or congenital malformations. The causality of the noticed associations can’t be established because of the potential for unmeasured residual confounding linked to the underlying illness.

In utero exposure to antipsychotic medication and psychiatric outcomes in the offspring.

Momen NC, Robakis T, Liu X, Reichenberg A, Bergink V, Munk-Olsen T.  Neuropsychopharmacology. 2022 Feb;47(3):759-766. 

The examine doesn’t present proof of elevated threat of psychiatric issues amongst kids of women who proceed antipsychotic remedy throughout being pregnant. 



Antenatal screening timeline and cutoff scores of the Edinburgh Postnatal Depression Scale for predicting postpartum depressive symptoms in healthy women: a prospective cohort study.

Tanuma-Takahashi A, Tanemoto T, Nagata C, Yokomizo R, Konishi A, Takehara Ok, Ishikawa T, Yanaihara N, Samura O, Okamoto A.  BMC Pregnancy Childbirth. 2022 Jun 28;22(1):527. 

An EPDS rating of 5 or higher on the second trimester might predict postpartum depressive signs.

Antidepressant discontinuation before or during pregnancy and risk of psychiatric emergency in Denmark: A population-based propensity score-matched cohort study.

Liu X, Molenaar N, Agerbo E, Momen NC, Rommel AS, Lupattelli A, Bergink V, Munk-Olsen T.

PLoS Med. 2022 Jan 31;19(1):e1003895.

In this examine, discontinuing antidepressant medicine throughout being pregnant (however not earlier than) is related to an obvious elevated threat of psychiatric emergency in comparison with persevering with remedy all through being pregnant.

Cognitive processing of emotional information during menstrual phases in women with and without postpartum depression: differential sensitivity to changes in gonadal steroids.

Bloch M, Helpman L, Gilboa-Schechtman E, Fried-Zaig I.  Arch Womens Ment Health. 2022 May 9. 

Women with hPPD reveal a differential bias in cognitive processing of emotional info that’s menstrual part dependent, and didn’t correspond to comparable distinction in temper signs. These biases might replicate sensitivity to gonadal steroid fluctuations which can be related to PPD.

Interpersonal therapy versus antidepressant medication for treatment of postpartum depression and anxiety among women with HIV in Zambia: a randomized feasibility trial.

Spelke MB, Paul R, Blette BS, Meltzer-Brody S, Schiller CE, Ncheka JM, Kasaro MP, Price JT, Stringer JSA, Stringer EM.  J Int AIDS Soc. 2022 Jul;25(7):e25959.

IPT and antidepressant medicine each improved measures of despair severity; nonetheless, a full-scale trial is required to find out whether or not remedy of PPD and nervousness improves maternal-infant HIV outcomes.



Monitoring of lamotrigine concentrations in mothers, colostrum, and breastfed newborns during the early postpartum period.

Kacirova I, Grundmann M, Brozmanova H.  Biomed Pharmacother. 2022 Jul;151:113167. 

Exposure to lamotrigine in breastfed newborns is decrease than publicity throughout being pregnant. However, lamotrigine concentrations in each maternal serum and milk improve considerably after supply.



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The long-term impact of elevated C-reactive protein levels during pregnancy on brain morphology in late childhood.

Suleri A, Blok E, Durkut M, Rommel AS, Witte L, Jaddoe V, Bergink V, White T.  Brain Behav Immun. 2022 Jul;103:63-72.

This examine discovered a direct affiliation between steady maternal immune activation (MIA) and decrease cerebellar quantity. In women, we demonstrated a detrimental oblique affiliation between steady MIA and whole mind quantity, by way of the mediator gestational age at delivery. 



Efficacy of cognitive therapy and behavior therapy for menopausal symptoms: a systematic review and meta-analysis.

Ye M, Shou M, Zhang J, Hu B, Liu C, Bi C, Lv T, Luo F, Zhang Z, Liang S, Feng H, Qian C, Cao S, Liu Z.  Psychol Med. 2022 Feb;52(3):433-445.  

CTBT is an efficient psychological remedy for menopausal signs, with predominantly small to reasonable results. The efficacy is sustained long-term, though it declines considerably over time. The efficacy was stronger for pure menopause signs, resembling vasomotor signs, than for treatment-induced menopause signs. 



SARS-CoV-2 during pregnancy and associated outcomes: Results from an ongoing prospective cohort.

Molenaar NM, Rommel AS, de Witte L, Dolan SM, Lieb W, Ibroci E, Ohrn S, Lynch J, Capuano C, Stadlbauer D, Krammer F, Zapata LB, Brody RI, Pop VJ, Jessel RH, Sperling RS, Afzal O, Gigase F, Missall R, Janevic T, Stone J, Howell EA, Bergink V.  Paediatr Perinat Epidemiol. 2022 Jul;36(4):466-475. 

Seropositivity for SARS-CoV-2 with out RT-PCR positivity at supply (suggesting that an infection occurred earlier throughout being pregnant) was not related to chosen adversarial maternal or neonatal outcomes amongst reside births in a cohort pattern from New York City.

The influence of structural racism, pandemic stress, and SARS-CoV-2 infection during pregnancy with adverse birth outcomes.

Janevic T, Lieb W, Ibroci E, Lynch J, Lieber M, Molenaar NM, Rommel AS, de Witte L, Ohrn S, Carreño JM, Krammer F, Zapata LB, Snead MC, Brody RI, Jessel RH, Sestito S, Adler A, Afzal O, Gigase F, Missall R, Carrión D, Stone J, Bergink V, Dolan SM, Howell EA; Krammer Serology Core Study Group.  Am J Obstet Gynecol MFM. 2022 Jul;4(4):100649.

Neighborhood measures of structural racism had been related to each elevated threat of SARS-CoV-2 an infection and better charges of preterm delivery, however these associations had been impartial and didn’t have a synergistic impact. 

The sexual and reproductive health of women with mental illness: a primary care registry study.

Hope H, Pierce M, Johnstone ED, Myers J, Abel KM.  Arch Womens Ment Health. 2022 Jun;25(3):585-593. 

Compared to women with out psychological sickness, women with psychological sickness had been extra more likely to expertise recurrent miscarriage (adjOR = 1.50, 95percentCI 1.41 to 1.60), termination (adjOR = 1.48, 95percentCI 1.45 to 1.50), gynaecological ailments (adjHR = 1.39, 95percentCI 1.37 to 1.40), sexually transmitted infections (adjHR = 1.47, 95percentCI 1.43 to 1.51), reproductive cancers (adjHR = 1.10, 95percentCI 1.02 to 1.19), contraception (adjHR = 1.28 95percentCI 1.26 to 1.29) and emergency contraception (adjHR = 2.30, 95percentCI 2.26 to 2.34).

Shared genetic basis between reproductive behaviors and anxiety-related disorders.Ohi Ok, Kuramitsu A, Fujikane D, Takai Ok, Sugiyama S, Shioiri T.  Mol Psychiatry. 2022 Jun 24.

This examine means that those that have earlier sexual debut and childbirth are vulnerable to threat for nervousness issues and vice versa, whereas those that have later sexual debut and childbirth are genetically vulnerable to threat for OCD. 


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